JollyGood Sans- the sensible alternative to the font that must not be named.
(I know I'm late to the game- After more than a years' work, Comic Neue beat me by a few weeks :( )
A while ago I decided to stop mocking comic sans and instead do something about it. I created JollyGood Sans as a replacement that would keep the fun, informal, handmade feel of CS, but with a more polished look (seriously, have you taken a close look at the capital H in CS?).
The result is a family of 11 fonts (more on the pipeline) that are legible, web-friendly, and have very complete character sets, including ligatures and alternate letterforms.
I hope it gives designers an alternative for when a comicsans-ish touch is needed.
JollyGood Basic is free, the rest are 60% off for a limited time.