Most of their typography is derived from modifying existing typefaces. If you give a specific example I'm sure someone here could sort it out.

It’s probably what they use throughout their site: ITC Serif Gothic, but with an extra thick outline stroke added.

Thanks a lot ... It works=)

I made my avatar probably in the same way they do their stuff.
It's basically a heavily modified sans serif. Although they also do serifs, but those looks kinda odd.

Thanks once again... spend several hours to observe all the pages.

How long does it take you to develop one of your custom typefaces?
JF: It depends on the typeface. Sometimes we work quite quickly and they’re exactly what we want for the job. Others need more work.
KE: Some won’t be the whole alphabet either, just the letters that you need. Then later you might go back to them.
JF: It might look great for the letters you need but might not for the rest of the alphabet. We had that with the Wire – we hoped and prayed that they wouldn’t write a headline with a Z in it! We didn’t have one.

Source: CR Blog

The new non-format book includes citations for all the fonts used.